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KMID : 0043319790020020153
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Archives of Pharmacal Research
1979 Volume.2 No. 2 p.153 ~ p.157
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Studies on the Constituents of Higher Fungi of Korea (XXVIV) Chemical Analysis of Antineoplastic Components of Coriolus versicolor (L. ex Fr.)Quel., Pleuroteus ostreatus (Fr.)Kummer, and Lentinus edodes (Berk.)Sing.
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Park EK
Choi EC/Kim BK
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Abstract
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The carpophores of three Korean mushrooms, Coriolus versicolor, Pleurotits ostreatits, and Lentitius edodes were respectively extracted with hot water and the extracts were dialyzed through Visking tube. They were found to contain an antitumor activity against sarcoma-180 implanted in mice. The components of these aqueous extracts were found to be polysaccharide and protein by color reactions including anthrone and Lowry-Folin tests. The hydrolysis of the polysaccharide with 3% HCl-MeOH and trimethylsilylation yielded four monosaccharides: glucose, mannose, galactose and xylose which were identified by G.L.C. After hydrolysis of protein with 6N HCl, fourteen to seventeen amino acids including aspartic and glutamic acids were detected by an amino acid analyzer.
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